Best way to operate two separate LTC wallets on the same computer?

In the past I’ve kept two separate wallet.dat files, but I’ve heard that’s risky — is there a better, safer way to do this?

submitted by _nightengale_
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from Litecoin: Open source P2P digital currency http://www.reddit.com/r/litecoin/comments/1uag2p/best_way_to_operate_two_separate_ltc_wallets_on/